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[Drug Discovery Chemistry Platform Unit] Unit Leader, Yoshinobu Hashizume

- Refining drug compounds -


" To create the most effective drug "

 After finding a promising compound, it is evaluated from every conceivable perspective, including efficacy, toxicity, absorption, distribution and excretion. In this way, we optimize the compounds for use as drugs. In this process, we utilize structure-based drug design (SBDD), which involves the three-dimensional mapping of the target protein's molecular structure. Through reevaluation of the results of experiments, and numerous repetitions of the synthesis and evaluation processes, the potential of the drug candidate gradually becomes clearer.


[Contact information for research-related enquiries]
Yoshinobu Hashizume TEL 048-467-4206 Mail 
[Contact information for non-research-related enquiries]
Rie Osaki TEL 048-467-9253 Mail